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Werth VP, Culton DA, Concha JSS, Graydon JS, Blumberg LJ, Okawa J, et al
The psychological work matters
A study published in Biology analyzing GLP-1 receptor signaling found elevated reporting odds ratios for dry mouth across the entire drug class, with tirzepatide showing a ratio of 1.35
Because all SMA patients have 1 or more SMN2 gene copies, small molecule compounds that target SMN2 to produce increased quantities of full-length SMN protein from the existing SMN2 gene(s) are attractive therapeutic candidates
This ne'w strategy may be based on the modulation of the hypothalamic/pituitary axis, the local administration of pituitary hormones and growth factors, or the stimulation of androgen responsiveness by AR penile gene therapy
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