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Nutritional intervention is expected to become the third major treatment modality alongside physical therapy and drug therapy, bringing significant benefits to patients with mild to moderate OA and effectively reducing the proportion of severe OA patients, which allow more people to avoid the adverse effects of repeated drug treatment and the potential risks of surgery and prosthesis replacement

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Glutathione reductase (GR) GR (E.C.1.6.4.2) is a flavoprotein oxidoreductase which uses NADPH as a reductant to reduce GSSG to GSH