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Oxidative stress from free radicals leads to cell damage and faster cellular degeneration, accelerating the aging process

Microcystins primarily activate signaling pathways such as the ERK/JNK/p38 MAPK and IL-6-STAT3 pathways, which trigger oxidative stress and could potentially contribute to carcinogenesis [87]

Shown to boost Glutathione levels in ethanol-induced rats, it was discovered that milk thistle could actually help protect the liver from toxicity after consuming alcohol - which is known to cause Glutathione levels to plummet

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Thus, indicating that inflammation is not robust in brains from elderly female mice with history of liver injury