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GLP-1R overexpression can inhibit the expression of inflammatory factors such as IL-6, IL-8, TNF- and granulocyte and macrophage colony-stimulating factor (GM-CSF) by increasing the expression of adenosine triphosphate-binding cassette transporter A1 (ABCA1) and reduce the proliferation and migration of smooth muscle, indicating that GLP-1R can play a protective role in smooth muscle cells and COPD, thereby improving airway inflammation and airflow limitation in COPD patients, providing a basis for the application of GLP-1RA in COPD

Supports mitochondrial fatty acid transport and energy metabolism

[DOI] [PubMed] [Google Scholar] 52.Demos K.E., Sweet L.H., Hart C.N., McCaffery J.M., Williams S.E., Mailloux K.A., Trautvetter J., Owens M.M., Wing R.R

Yu, Parkinsons disease derived exosomes aggravate neuropathology in SNCA*A53T mice

The wegovy tablet, now available in Texas, is taken orally each morning, providing the same benefits as the injectable version