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Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I: Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

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This cascade promotes inflammation in various tissues, and contributes to CVD, fatty liver disease, and even neurodegeneration (Figure 2)

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