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Treatment was initiated in mice when they displayed clinical signs characteristic of intestinal tumour burden as defined in the relevant licensing documents (for example, hunching, bloody stools)

Mechanistic insights from animal models reveal that the abundance of Bacteroidota was negatively correlated with the levels of IL-1, TNF-, and malonaldehyde (MDA) and positively correlated with the levels of CAT and GSH

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Additional studies have highlighted the neuroprotective effects of other natural compounds, such as benzyl ITC and indole-3-carbinol (not an ITC, but derived from indole glucosinolates), in preclinical models of PD

Scientific literature suggests glutathione plays a key role in hepatic detoxification and antioxidant defense