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The bioavailability of supplemental acetyl-L-carnitine has not been as well studied, though some evidence suggests slightly higher circulating concentrations compared to equivalent L-carnitine doses, with peak plasma levels typically achieved 24 hours after oral administration [5][12]

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Our aim was to investigate dopamine- and ibuprofen-coupled 3-armed poly(l-glutamic acid) nanocarriers targeted by A-GSH for transfer across a novel human co-culture model with induced BBB properties