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14913991407.e210.1053/j.gastro.2015.07.054 Gastroenterology 17 BonavitaV.De SimoneR

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Specifically, ABCF1-K430la in HCC tissues enhances the dimethylation of H3K9 (H3K9me2) through binding with the KDM3A promoter and upregulating its expression, subsequently regulating HIF1A and the accompanying lactate production

Alcohol is a known gastric irritant that triggers inflammation of the stomach lining and increases acid production