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Several potential mechanisms have been proposed, though evidence specifically linking them to panic symptoms with Wegovy is limited: Increased heart rate : GLP-1 receptor agonists can increase heart rate, which may be perceived as anxiety or palpitations Hypoglycaemia : Though uncommon with Wegovy alone in people without diabetes, low blood sugar can trigger anxiety-like symptoms (risk increases if taking insulin or sulfonylureas) Gastrointestinal distress : Severe nausea or abdominal discomfort may provoke anxiety or panic responses in susceptible individuals Individual susceptibility varies considerably

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doi:10.1016/j.cld.2013.07.002 [PMC Full Text] [PubMed] [Crosslink] Harshad Devarbhavi, Raj S, Aradya VH, et al