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This helps in minimizing potential side effects

Therefore, GLUTag cells were transduced with control, hGPR17L-WT, hGPR17L-V96M, and mGPR17 with multiplicities of infection that provided similar receptor expression levels as measured by immunofluorescence imaging using an -HA antibody (Figure 4A)

In order to rule out direct glucose effects on the macro- and microvascular event rate, glucose parameters are kept as closely overlapping as possible ( So far four studies for cardiovascular safety studies have been completed and published: The EXAMINE (Examination of Cardiovascular Outcomes with Alogliptin vs