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MS: Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing original draft, Writing review & editing

Nonresponse to heart failure therapy

While circulating levels of PYY 3-36 are frequently reduced in individuals with obesity 31,32,33,34,35 , these levels typically return to those detected in average-weight individuals following a reduction in body weight and/or gastric bypass surgery 32,33,35

They were especially important in identifying cardiovascular effects such as increased heart rate, and assessing gastrointestinal tolerability