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This dynamic equilibrium enables precise control of the cellular redox state

Pre-treatment of human and rat serum and urine samples Concentrations of L-CN and GBB in plasma and urine were determined in humans and rats using UHPLC/MS as previously described with minor modifications

The nine dinucleotide loci (CpG1, CpG2, CpG3, CpG4, CpG5, CpG6, CpG7, CpG8, CpG9) in the GSTA4 promoter region (Chr6:52,977,953-52,995,284, GRCh38/hg38) were selected for DNA methylation pyrosequencing (Figure 1)