A small cholesterol-like compound, olesoxime, has been shown to promote oligodendrocyte maturation, remyelination, and functional recovery in rodent models of demyelination, via binding to mitochondria and the modulation of ROS levels (Magalon et al., 2012, 2016)
A supplement is often recommended to offset the risk of deficiency (which has been associated with everything from poor bone health to increased mortality
The honest summary: the in vitro mechanism is increasingly well-supported and now has independent replication
Why we dont recommend counting calories While there can be some benefit to understanding how many calories youre eating each day, we dont recommend calorie counting
It does not predict semaglutide response, but it informs the conversation