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By improving the integrity of the gut lining and reducing gut-derived inflammation, BPC-157 could theoretically help improve insulin sensitivity and overall metabolic function

However, regardless of their definite positive effects, therapeutic applications of natural neurotrophins like NGF and BDNF, for treatment of neurodegenerative diseases, are limited due to their inability to cross blood brain barrier and also susceptibility to degradation by peripheral peptidases (Tomioka et al., 2014)