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CRH immunoreactivity is mainly found in the paraventricular nuclei (PVN) of the hypothalamus, often co-localized with AVP (51)

That is, EGT could couple GSH to reduce ferryl myoglobin, chelate transition metal iron to scavenge ROS/RNS and free radicals generated during IR, regulate proinflammatory cytokines like interleukin-1 (IL-1) and tumor necrosis factor- (TNF-), and ultimately prevent myocardial injury (Servillo et al., 2017a)

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doi: 10.1155/2022/9097530 276 XuYTangXFangAYanJKofi Wiredu OcanseyDZhangXet al

FOXO4-DRI, despite modification, continues to influence gene expression and key cellular processes