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Under PCAC review since October 2024

Efficacy signal: Trial data shows tirzepatide achieves 20.9% average weight loss (SURMOUNT-1) versus semaglutide's 14.9% (STEP 1), but individual outcomes vary and no obesity-specific switching trial exists yet

Comparing semaglutide to other medications commonly injected incorrectly Semaglutide is not unique in being accidentally injected into the wrong tissue layer

To investigate whether the three mAbs (3G10, 5C6, and mAb234) target the same or overlapping sites in the capsid, we performed competitive ELISA using PV1 sVLP as the coating antigen

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