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Prior to that, the company had committed $500M into an active pharmaceutical ingredient (API) plant in Ireland, $1.6B to expand its new manufacturing sites in Indiana, and $1.7B over three years for the expansion of their fill-finish sites at Research Triangle Park, NC and Concord, NC

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The data for altered genes in CM are average from Akbanis and Haywards papers (79), while the figures for MM are obtained from Newells paper ( Figure 2 summarizes the frequency of alterations in possible driver genes based upon WGS data of 67 frozen tumors ( Figure 2 Table 2 Comparison of genetic profiles MM and CM