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3.6 Anti-inflammatory effects of GO@GSH-FA in OGD/R-induced SH-SY5Y cells To elucidate the potential anti-inflammatory role of GO@GSH-FA in ischemia-induced cellular damage, we quantitatively assessed the levels of key proinflammatory cytokines, namely Tumor Necrosis Factor- (TNF-) and, Interleukin-1 (IL-1) in SH-SY5Y cells subjected to oxygen-glucose deprivation and reoxygenation (OGD/R) and treated with GO@GSH-FA

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Therefore, targeting tumor methionine metabolism could be a promising strategy to antagonize T cell exhaustion in the tumor microenvironment

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