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The ACJ has a small volume and I thus perform ACJ injections using an orange needle with a smaller volume of local

Animal studies confirm that chronic high-fat diet impairs hypothalamic lipid sensing, a dysfunction that can be ameliorated to control feeding behavior by reducing LCFA oxidative metabolism (Pocai et al., 2006), while more recent evidence highlights the critical role of specific neuronal nutrient sensors in this process (Niazpour and Meshkani, 2025)

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