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GLP-1 has also been demonstrated to decrease lactate and pyruvate concentrations, thereby providing another mechanism for cardioprotection via improvement in metabolism [53]

Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinsons disease trial

Human studies in post-gastroenteritis and postbariatric surgery settings have observed transient increases in GLP-1 and peptide YY (PYY), potentially related to mucosal stimulation and altered gut motility [3-5]

We reason that in chronic obesity, sustained GLP-1 activation in Tmprss2 / mice improves insulin sensitivity and glucose metabolism but, at the same time, paradoxically regulates insulin-induced GIP secretion independent of PAR2 signaling, thus superseding TMPRSS2 deficiency

The digestive disruption might be more noticeable