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Individuals with an intact blood-brain barrier (BBB) are usually protected from higher dietary intake of free glutamate due to saturation of the glutamate transporter at the BBB, thereby limiting the amount of glutamate able to access the CNS (64)

Initial observations suggest that MC3R might be involved in modulating appetite under certain experimental conditions

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Gler of the University of Virginia

However, it is essential to note that excessive consumption of L-Carnitine can lead to side effects such as nausea, vomiting, and diarrhea