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3A, in the MR results of the discovery cohort (GWAS catalog), increased expression of GLP-1R in blood tissues corresponded to a significantly lower risk of developing DR (IVW: OR = 0.47, 95%CI: 0.310.70, P = 0.0003), and the heterogeneity test results of the IVW method ( P = 0.3196) and the MR-Egger regression method ( P = 0.6167) indicated that heterogeneity was not significant and could be ignored

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Protoplasma 223:213219 Munyampundu JP, Xu YP, Cai XZ (2016) Phi class of glutathione S -transferase gene superfamily widely exists in nonplant taxonomic groups

Although the predominance of available literature from in vivo ischemic studies has focused on the involvement of synaptic vesicle zinc, it is likely that intracellular zinc accumulation during ischemia is achieved through a possible synergism of zinc release from both synaptic and intracellular stores of zinc, as most recently demonstrated during global ischemia (38) and reported in other experimental paradigms (4551)