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Those who've had certain surgeries: Gastrointestinal surgeries may reduce intrinsic factor production, limiting B12 uptake from food or oral supplements

This may mean that ROS may be responsible, or it may be a contributory factor to the in- fertility been experienced by such individual

People with a prior history of gastrointestinal problems and aged individuals are more likely to suffer from intense stomach cramps and severe diarrhoea after taking high doses of vitamin B. Most people are able to get enough vitamin B12 from their diets, however, occasionally when running low, supplements or B12 injections may be recommended

[2] He worked as a postdoctoral researcher for Guarente for four years and in 1999 he was hired at Harvard Medical School