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Ras stabilization through aberrant activation of Wnt/-catenin signaling promotes intestinal tumorigenesis[J]

Notably, the PtMnIr nanozyme exhibits multiple enzymatic activities, integrating OXD, CAT, SOD, POD, and GPX functionalities, thereby promoting ferroptosis and apoptosis in tumour cells while inhibiting tumour metastasis by establishing an endogenous GSH consumptionROS cyclic generation mechanism [139]

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However, accumulating evidence has identified additional GI complications, including cholelithiasis, cholecystitis, gastroparesis, and bowel obstruction, which may warrant caution in susceptible individuals

Glutathione is a tripeptide, which is a small protein-like molecule made of three specific amino acids: glutamic acid , cysteine , and glycine