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The introduction of the R17 Cagri- E14 Cagri intra-peptide ionic lock energetically favours the formation of a predominant bypass conformation at the CTR, which, together with the P37 substitution and the effects induced by the N-terminal acylation, likely underlies its improved potency over rAmy at this receptor

To further substantiate our working model, we re-analyzed the data obtained in our previous study showing that the silencing of LDHB results in a significant reduction in mitochondrial metabolism 11

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A critical appraisal of vitiligo etiologic theories