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Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al

The accumulation of histamine can result in various symptoms ranging from mild to severe, including migraines, gastrointestinal problems, and skin rashes

Examining the adaptive processes that are established to respond to the initial CS burden may help to understand what pathways become defective or are compromised and may contribute to the pathogenesis of COPD