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This pathway controls how cells convert nutrients into usable energy and helps maintain metabolic balance under varying energy demands
Neurons were held at 60 mV in current clamp mode, and ramps of depolarizing current (1-s duration, peak amplitudes of 100, 300, 500 and 700 pA) were injected into each neuron
Endocrinology 156 , 847857 (2014)
The cytotoxic effect of erastin was dose-dependent, with erastin (11 M) showing a decrease in cell viability, and 14 M showed a significant decrease in cell viability compared with 8 M and below ( Figure 1A )
Subsequent studies expanded into musculoskeletal healing, vascular biology, and regenerative medicine
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