glp-1 and crohn's GLP-1s Disease: Safety, Biomarkers, and Provider G... – PlexusDx GLP-1 RAs and Crohn's Disease

There are limited data to indicate that hormone therapy may stimulate the growth of residual ovarian or endometrial tissue after total hysterectomy and bilateral salpingo-oophorectomy if all visible disease was removed (42)

The limited repair capacity of sperm makes them highly susceptible to accumulating DNA damage, particularly in the context of oxidative stress

This means the B12 component in a compounded semaglutide formulation is most likely to help patients who are deficient or at risk of deficiency, those eating very little, those following plant-based diets, older adults whose B12 absorption decreases with age, or those with conditions affecting B12 absorption like gastric bypass or certain GI conditions

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Cost considerations: GLP-1 RAs are generally covered by insurance for diabetes, often not for obesity