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Partial remission with this combination ended after 7 months, when liver metastases were detected sonographically

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This observation means that xCT blockage induces the accumulation of glutamate that is converted into -ketoglutarate instead of being used in glutamate-cysteine exchange and consequently that is why cysteine does not enter the cell and give rise to glutathione

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Clinical Chemistry , 1997, 43: 141-145

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39 YeL.HuangY.ZhaoL.LiY.SunL.ZhouY.et al (2013)

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