Chen X, Zhi F, Jia X, Zhang X, Ambardekar R, Meng Z, et al
High doses, repeated administration, vulnerable populations (pregnant animals), and sensitive tissues (gastrointestinal tract, reproductive organs) have all been evaluated
Hot flashes can be one of the most uncomfortable and disruptive symptoms for women going through menopause
It incorporates the prediction of oral toxicities of chemicals which can be measured at different levels of toxicity mainly qualitatively in terms of endpoints as binary output (active or inactive) along with confidence scores such as acute toxicity, hepatotoxicity, carcinogenicity, immunotoxicity, mutagenicity, cytotoxicity, adverse outcome (Tox21) pathways, and toxicity (LD50) values in mg/kg body weight
Intramedullary MSs (IMSs) are even rarer lesions, with only 12 cases of IMSs reported in the literature as of 2022