In patients with severe hepatic or renal disease, effects of therapy should be followed with serial liver and/or renal function tests
A safer sequence is to reduce ongoing exposure, restore hydration and nutrition, correct bowel dysfunction, evaluate organ safety, address biochemical deficiencies and then retest before escalating treatment
Levo-carnitine helps turn the fats present in ingested food into energy
Some studies have evaluated the effect of co-administration of caffeine with other substances, such as caffeic acid at 15 mg.kg -1 or 10 mg.kg -1 [34], coffee and decaffeinated coffee at 140 mg.kg -1 each [32], instant coffee powder at 0.5 ml/100 g and decaffeinated coffee at 200 mg.kg -1 [38], and green tea [35]
This reduces the levels of melanin, a pigment that is responsible for the skin color, hence making the skin lighter in color