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[167] In January 2024, a preliminary review conducted by the US Food and Drug Administration (FDA) confirmed no evidence had been found to suggest that the medicine causes suicidal thoughts or actions

TFR1 has a 30-fold higher affinity for transferrin-bound iron than TFR2 and thus is the main player in this process

This is why the manufacturing quality of compounded tirzepatide is not a secondary concern

This ensures the highest standard of quality and efficacy

Additionally, there have been reports of diabetic retinopathy complications , particularly in patients with pre-existing retinopathy who experience rapid improvements in glycaemic control