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Semax (ACTH 4-10 analogue) upregulates acetylcholine release and increases brain-derived neurotrophic factor (BDNF), producing enhanced focus and working memory through cholinergic and dopaminergic pathways

This retrograde signaling mechanismmitochondria communicating upstream to the nucleusis what Brnice Benayoun, a faculty member at USC Leonard Davis and co-author on the Reynolds et al