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Meta-analyses across these studies affirm class effects: HF composite HR 0.84 and renal HR 0.82 [74, 75]

Diagnoses are confirmed by a blood test that looks for specific genetic differences in the q11.2-q13 region of chromosome 15 that are seen in individuals with PWS

Muscle carnitine was evaluated in 2 studies (Rudman et al., 1977

Sussman MA, Vlkers M, Fischer K, Bailey B, Cottage CT, Din S, Gude N, Avitabile D, Alvarez R, Sundararaman B, Quijada P, Mason M, Konstandin MH, Malhowski A, Cheng Z, Khan M, McGregor M: Myocardial AKT: the omnipresent nexus

One often overlooked factor in the success of TRT is the type of provider overseeing the treatment