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doi:10.1111/dom.14275 Cava E, Yeat NC, Mittendorfer B

The medication is absorbed in the stomach before bile plays any significant role, and its systemic effects do not depend on bile storage or release

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor

Endothelial plasticity drives arterial remodeling within the endocardium after myocardial infarction

Metabolic and endocrine changes, including restoration of menstrual cyclicity or improvement of hyperandrogenism, have also been investigated as secondary outcomes