You've likely heard of GLP-1 medications powerful drugs like Ozempic, Wegovy, and Mounjaro making waves in the world of weight management and diabetes care
With the right medical support, evidence-based treatment, and commitment to your health, meaningful transformation is possible
Abbreviations ASCVD: Atherosclerotic cardiovascular disease CHD: Coronary heart disease CI: Confidence interval CVD: Cardiovascular disease CVOT: Cardiovascular outcome trial DPP-4i: Dipeptidyl peptidase-4 inhibitor GLP-1: Glucagon-like peptide 1 GLP-1R: Glucagon-like peptide 1 receptor HbA1c: Glycated haemoglobin HR: Hazard ratio LDL: Low-density lipoprotein MACEs: Major cardiovascular events NO: Nitric oxide OR: Odds ratio PIONEER: Peptide Innovation for Early Diabetes Treatment ROS: Reactive oxygen species SC: Subcutaneous SNAC: Sodium N -[8-(2-hydroxybenzoyl)amino] caprylate TAGs: Triacylglycerols TGs: Triglycerides T2DM: Type 2 diabetes mellitus VLDL: Very-low-density lipoprotein References Litwak L, Goh SY, Hussein Z, Malek R, Prusty V, Khamseh ME
Seven-hundred nineteen patients (70%) were excluded due to prescription insurance denial, inability to use the medication due to the national shortage in 2021 and 2022, and less than 3 months of medication use
When combined with your clinical biomarkers (glucose, insulin resistance, lipids) and treatment goals, this genetic predisposition data can inform personalized dosing and compound selection strategies