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GLP-1-derived peptides regulate rat and human TRPV1 activation independently of GLP-1R expression To verify the potential involvement of GLP-1R in the observed inhibitory effects on TRPV1 channels, we transiently transfected rat TRPV1 into HEK293T cells

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Injection Site Reactions Mild redness, itching, or tenderness at the injection site Usually resolves within 2448 hours Rotating sites (abdomen, thigh, upper arm) and allowing the pen to reach room temperature before injecting reduces reactions Serious Side Effects When to Call Your Doctor Immediately These are uncommon but require immediate medical attention