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(2014) 306:H36372

Myoblast Proliferation and Anti-Differentiation Yang and Goldspink (2002) in FEBS Letters the foundational paper for synthetic MGF E-peptide research confirmed that MGF E-domain peptide increases myoblast proliferation while inhibiting terminal differentiation of C2C12 cells, in contrast to mature IGF-1 which primarily promotes differentiation with a lesser proliferative effect

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