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Activated astrocytes can shift toward different phenotypes: the A1 type, induced via NF-B signaling, produces proinflammatory mediators and can trigger neuronal apoptosis, whereas the A2 phenotype, driven by STAT3 activation, promotes anti-inflammatory and neuroprotective responses [32]

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Some people lose muscle during GLP-1 treatment because appetite drops, total food intake decreases, and protein intake may become too low

e , Crystal packing of GLP-1RPF-06372222, with the two molecules per asymmetric unit coloured green and cyan, respectively

Scientists are exploring its applications in tissue repair, nerve regeneration, and hair growth stimulation