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Thus, the participants selected in these two clinical trials may have been those with the most severe metabolic abnormalities and most expected to respond to these treatments

This has several positive effects, two of which are the prevention of extreme and unhealthy GH levels in the body and the mirroring of more natural patterns of fluctuation in GH concentrations

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Review Article OPEN ACCESS Madhumitha Rondla 2 , Karthik Muralidharan 1 and Sun-Joo Jang 1,* Author information Abstract Obesity is a global health burden and is closely associated with severe chronic co-morbidities, which remain the leading causes of death