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[107:54] Andrew Huberman The effects of endogenous and perhaps also exogenous hormones

2005;57(6):77380 Younes N, Cleary PA, Steffes MW, de Boer IH, Molitch ME, Rutledge BN,

Collectively, these data indicated that the more pronounced weight loss phenotype of PAR2-G37I versus PAR2-R38E mice is not explained by differences in ATM or adipose tissue endothelial cell reprogramming

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These investigators found that obese patients who had heart failure with preserved ejection fraction, semaglutide significantly reduced the risk of the combined endpoint of cardiovascular death or worsening heart failure events (HR 0.69, 95% CI 0.530.89), and worsening heart failure events alone (HR 0.59, 95% CI 0.410.82) [50]