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ESSENCE Phase 3 semaglutide in MASH data supported FDA approval in March 2024 , creating a premium pricing tier in a disease category with USD 17.4 billion addressable market and no prior approved pharmacotherapy

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Additionally, cellular repair processes like autophagy become more active, potentially supporting longevity and cellular health

118 Reisi et al reported that both presynaptic and postsynaptic components are involved in diabetes-induced damage to synaptic plasticity