Halperin understands that people might be tempted to seek out lower-cost alternatives, but she recommends that patients work with a healthcare provider who has experience in treating obesity, even if they cant get access to a specific medication at the moment
"If you don't go to the gym and train while you're on these drugs, you just eat less shitty food and you take your already-low levels of muscle mass and dump them even further." "There's a situation people have described called 'Ozempic ass' and it's women who just diet their butts literally off totally flat." "It's a problem you've never seen exposed before because most of those people would have never dieted the weight off to begin with." Mr Curtis said, in his experience too, people with personal trainers are able to retain muscle while using semaglutide
On December 11, 2025, Eli Lilly published topline Phase 3 TRIUMPH-4 results
Consistency week to week helps keep the medication working steadily
For semaglutide, median weight loss increased from approximately 56% at 1.0 mg to around 10% at 2.4 mg, with further reductions observed at 7.2 mg
