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Hypertension 75(6):13341357

Nieto Y, Ward JF, Hofstetter W , Rice D, Karam JA, Pisters L, Vauthey JN, Shah A, Lin JK, Johns AC, Araujo J, Tu SM, Wang J, Li J, Abudayyeh A, Thall PF, Bassett R, Barnett M, Gulbis A, Shigle TL, Ramdial J, Popat U, Qazilbash M, Jones RB, Andersson BS, Shpall EJ, Sheikh I, Pagliaro L, Campbell MT

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Several in vitro and in vivo studies have demonstrated that DPP-4 inhibitors possess antioxidant, anticancer, and proapoptotic properties, particularly against pancreatic and colon cancer cell lines (HT-29)

This is important because it may suggest patients with kidney disease have an inherent resistance to these hormones and that medications like Ozempic or Mounjaro that boost the effects of GLP-1 and GIP may be of particular benefit to those who tolerate them, Berglund added