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Biochemical Structure and Copper-Binding Mechanisms Molecular Architecture of the GHK-Cu Complex The GHK-Cu peptide complex exhibits a specific molecular weight of 340 Da, comprising the tripeptide backbone (Gly-His-Lys) coordinated with a single copper(II) ion

In antioxidant homeostasis, the condition, where there is excessive free radical species production and also a depletion of antioxidant capacity, is termed oxidative stress

Immunohistochemistry Fixed wing imaginal discs were stained with antibodies according to standard procedures

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The study established that FOXO4 maintains senescent cell viability by targeting p53 to the nucleus and preventing apoptosis, and that disrupting the FOXO4-p53 interaction with FOXO4-DRI causes p53 nuclear exclusion and cell-intrinsic apoptosis in ionising radiation-induced and doxorubicin-induced senescent IMR90 fibroblasts