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human studies report only mild, transient side effects (occasional headache or nausea)

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Solvent A is 40:40:20 acetonitrile:methanol:water with 0.1 M formic acid, and solvent B is 15% NH 4 HCO 3 in water (w:v), precooled on ice

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These studies reveal that GLP-1 RAs not only decrease oxidative stress and inflammation in endothelial cells but also inhibit cardiac hypertrophy and fibrosis by regulating myocardial proliferation and apoptosis [76]