how long have glp-1 drugs been around History: Has This Drug Used? Market Overview: GLP-1 Agonists and

( europepmc.org ) Broad regenerative / protective pathway influence: a major review summarised how GHK-Cu may influence multiple pathways involved in repair, inflammation, and oxidative stress (including gene expression data)

doi: 10.1038/jid.2012.261 271 KhlgatianMKHadshiewIMAsawanondaPYaarMEllerMSFujitaMet al

For two of these drugs, risperidone and venlafaxine, the active metabolites (paliperidone and desvenlafaxine, respectively) were marketed as drugs in their own right several years after the parent drugs were marketed

Dialed in

Notably, these advantages persisted irrespective of baseline kidney function, HbA1c levels, BMI, the timing of DM diagnosis, comorbidities and concurrent medication, including immunosuppressants (Fig