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strengthening and enhancement of biomedical research of the National Health Service (Sistema Sanitario Nazionale, SSN), funded by the European Union NextGenerationEU

Eventually, this may result in cell death from the destructive cellular programs

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27 Additionally, GSH is synthesized from cysteine via the System Xc (comprising SLC7A11 and SLC3A2) and the transsulfuration pathway, with GSH consumption leading to GPX4 inactivation