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What makes cagrilintide particularly interesting from a pharmacological standpoint is that it appears to produce a preferential loss of fat mass rather than lean mass a finding observed in preclinical and clinical studies

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The most common of them include Cu 2+ /Zn 2+ superoxide dismutase 1 ( SOD1 ), TAR DNA-binding protein 43 ( TARDBP) , fused in Sarcom a ( FUS ) , and chromosome 9 open reading frame 72 ( C9orf72) genes, involved in protein homeostasis and RNA metabolism [72,73,74,75]