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The therapeutic potential of natural extracts for treating AD has been thoroughly explored through both in vivo and in vitro studies

CHD, chronic heart disease

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471 Knocking down FTH in cardiomyocytes prevents free iron from being stored in ferritin, increases unstable iron pools, promotes intracellular ROS production, activates oxidative stress, and causes ferroptosis in cardiomyocytes, leading to age-related heart damage

Additionally, a high dosage of EPA (1.8 g/d) for 12 weeks could improve the psychological symptoms, and quality of life by alleviating the severity, frequency and disability of migraine attacks (135)